Impact of a Multimodal Lifestyle Intervention on Dementia Risk Factors and Attitude Related to Dementia Risk: A Logistical Pilot Study

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

May 2, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Cognitive ImpairmentAlzheimer Blood BiomarkersAlzheimer Disease (AD)Mild Cognitive Impairment (MCI)
Interventions
BEHAVIORAL

Multimodal Lifestyle Intervention

The intervention supports adoption and maintenance of healthy behaviors including healthy nutrition The Mediterranean-DASH (Dietary Approaches to Stop Hypertension) Intervention for Neurodegenerative Delay, or MIND Diet), physical activity (150 min/week of moderate activity), stress management, weight management, and adherence to doctor-prescribed medical regimens. In addition, participants will be encouraged to participate regularly in social and learning activities, and to engage in cognitive training via Posit's BrainHQ web-based training tools (brainhq.com). Participants will be supported by telephone-based health coaching. Coaches will be currently licensed allied health providers such as Registered Dietitians. Using the combination of an individual's biological data (including genomics, blood, stool, saliva, etc.), activity data, behavioral data, and other incoming streams of health information, the coach will tailor the lifestyle intervention for each participant.

Trial Locations (1)

35806

RECRUITING

Smith Family Clinic for Genomic Medicine, Huntsville

All Listed Sponsors
lead

HudsonAlpha Institute for Biotechnology

OTHER