106
Participants
Start Date
September 1, 2024
Primary Completion Date
January 1, 2025
Study Completion Date
January 1, 2025
Olive Oil Polyphenol Supplement (OOPs, OLEOPROTECT®, Thousand Olives®)
Participants receive two capsules daily (total 10 mg/day) of a standardized olive oil polyphenol extract. Each capsule contains 5 mg of aldehydic phenols: 75% oleocanthal/oleacein and 25% oleuropein aglycon/ligstroside aglycon. Formulated with PEG400, cellulose, silicon dioxide, and magnesium stearate. Duration: 12 weeks.
Placebo capsules
Two capsules taken daily for 12 weeks. Identical in weight, appearance, and taste to the active OOPs capsules. Contain PEG400, cellulose, silicon dioxide, and magnesium stearate, but no active olive oil polyphenols.
Apostolos Loukas Medical Centre Cyprus, Nicosia
University of Nicosia
OTHER
University of Crete
OTHER
National and Kapodistrian University of Athens
OTHER
Yale University
OTHER
Apostolos Loukas Medical Centre Cyprus
NETWORK