Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

November 13, 2025

Primary Completion Date

May 13, 2028

Study Completion Date

May 13, 2029

Conditions
Type 1 Diabetes Mellitus
Interventions
DRUG

Rezpegaldesleukin

Rezpegaldesleukin will be dosed at 12 μg/kg for subcutaneous injection. Rezpegaldesleukin will be provided as a 1.5 mg/mL sterile solution in a vial for injection preparation. Study agent injections will be administered in the abdomen, back of the upper arm or the upper thigh of the participant.

DRUG

Placebo

Sterile saline for injection. Placebo will be administered in the same volume and as the active comparator to maintain treatment masking.

Trial Locations (1)

37232

Vanderbilt University, Nashville

All Listed Sponsors
lead

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH