Adebrelimab Combine With Etoposide Capsules in ES-SCLC Maintenance Therapy

PHASE2RecruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

August 25, 2025

Primary Completion Date

December 30, 2026

Study Completion Date

December 30, 2027

Conditions
SCLC,Extensive Stage
Interventions
DRUG

Adebrelimab combined with Etoposide Capsules

Each treatment cycle spans 3 weeks. Sequential medication administration begins on the first day of each cycle: Adebrelimab is administered at a dosage of 1200mg on day 1, every 3 weeks, while Etoposide Capsules is given orally at a dosage of 50mg or 25mg daily, every 3 weeks. Administration timing allows for a window of ±5 days. Subjects are required to undergo comprehensive assessments, including vital signs monitoring, anthropometric measurements, physical examinations, laboratory analyses, and performance status evaluations, to assess treatment tolerability for continuation.

Trial Locations (1)

710000

RECRUITING

Tangdu Hospital Affiliated to the Fourth Military Medical University, Xi'an

All Listed Sponsors
lead

Tang-Du Hospital

OTHER

NCT07141264 - Adebrelimab Combine With Etoposide Capsules in ES-SCLC Maintenance Therapy | Biotech Hunter | Biotech Hunter