Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery

NANot yet recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

October 30, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

December 30, 2025

Conditions
Lumbar Disc HerniationEmergence AgitationMagnesium Sulfate
Interventions
DRUG

Magnesium Sulfate Infusion

Magnesium Sulfate (Experimental Group) Intravenous bolus of magnesium sulfate 30 mg/kg administered over 15 minutes immediately after induction of general anesthesia, followed by continuous infusion at 10 mg/kg/h until the end of surgery. Solutions were prepared in identical syringes and infusion bags by an anesthesia technician not involved in patient care. The preparation and administration protocol ensured blinding of participants, anesthesia providers, and outcome assessors.

DRUG

0.9% Saline Infusion

ntravenous bolus and continuous infusion of 0.9% sodium chloride solution in the same volume, infusion rate, and duration as the magnesium sulfate group. Solutions were indistinguishable in appearance and prepared under the same blinding procedures.

All Listed Sponsors
lead

Ondokuz Mayıs University

OTHER

NCT07139847 - Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery | Biotech Hunter | Biotech Hunter