TAP Block With Lidocaine and Ropivacaine 0.2% (0.4 ml/kg/Side) for Pain and Opioid Reduction After Hysterectomy

NAActive, not recruitingINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

January 12, 2024

Primary Completion Date

July 1, 2026

Study Completion Date

December 31, 2026

Conditions
Postoperative Pain Following Hysterectomy
Interventions
PROCEDURE

Pre-incisional Transversus Abdominis Plane (TAP) block performed under ultrasound guidance. The block will be administered bilaterally using a mixture of lidocaine and ropivacaine 0.2%

After the induction of general anesthesia, bilateral TAP block will be performed in patients from Group 1. The administered dose will include 0.2% lidocaine combined with 0.2% ropivacaine, at a dose of 0.4 ml/kg per side, without exceeding toxic dose limits per kg.

DRUG

Participants in this arm will receive standard analgesia for postoperative pain management following elective hysterectomy

Participants in this arm will receive standard multimodal systemic analgesia for postoperative pain management following elective hysterectomy. The regimen includes Paracetamol (oral or intravenous) 1g/24 hour, Ibuprofen IV 1200 mg/24 hour, or Parecoxib 80 mg/24 hour IV, and Tramadol 100 mg IV. Additional rescue doses of Tramadol (50-100 mg IV every 4-6 hours) may be administered based on pain intensity, with a maximum of 400 mg/24 hours (or 300 mg/24 hours for patients aged ≥75 years). No Transversus Abdominis Plane (TAP) block will be performed in this group. Pain intensity, opioid use, and postoperative recovery scores will be evaluated and compared with the TAP block intervention group.

Trial Locations (1)

540136

County Emergency Clinical Hospital of Targu Mureș, Târgu Mureş

All Listed Sponsors
lead

Matild Keresztes

OTHER

NCT07139691 - TAP Block With Lidocaine and Ropivacaine 0.2% (0.4 ml/kg/Side) for Pain and Opioid Reduction After Hysterectomy | Biotech Hunter | Biotech Hunter