Optimizing Linezolid Dosing in Patients With Advanced Renal Impairment: a Therapeutic Drug Monitoring-based Evaluation

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

October 15, 2025

Primary Completion Date

December 15, 2025

Study Completion Date

May 15, 2026

Conditions
Kidney Disease
Interventions
DRUG

Linezolid (IV and PO)

No dose change and continued linezolid 600 mg every 12 hours.

DRUG

Linezolid (IV and PO)

Intervention and adjustment of the linezolid dose from 600 mg every 12 hours to 300 mg every 12 hours.

DRUG

Linezolid (IV and PO)

Intervention and adjustment of the linezolid dose from 600 mg every 12 hours to 600 mg every 24 hours.

All Listed Sponsors
lead

Alexandria University

OTHER