Virtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans

NANot yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

August 31, 2027

Conditions
Chronic PainPTSD - Post Traumatic Stress DisorderQuality of Life (QOL)
Interventions
PROCEDURE

Virtual reality

The VR intervention will take place in a quiet room. The participant will be installed in a seated position, wearing a virtual reality headset that includes an audio device playing sounds. The eyes are covered by a mask featuring a screen showing calming 3D VR images (e.g. beach landscapes), designed by our team. The intervention lasts 20 minutes. The hypnotic suggestions with auditory and visual calming stimulations will help the person to focus on the present moment, to reduce anxiety and painful sensations.

PROCEDURE

Cranial nerve non-invasive neuromodulation (CN-NINM)

During each intervention including CN-NINM, this latter will be applied for 20 minutes, with the help of a portable stimulator comprising a network of 18 electrodes, directly on the tongue of the participants. The participants will hold the CN-NINM in place by pressing their tongue upwards. The CN-NINM will generate high-frequency pulses (50 µsec to 150 Hz), and the intensity of the stimulus will be set by each participant to a comfortable level of sensation, similar to the sensation in the mouth of a soft drink.

PROCEDURE

Sham CN-NINM

In this study, we will have a control intervention which will be placebo CN-NINM. For placebo CN-NINM, participants will wear the device such as the real CN-NINM group, without having experienced the tingling sensation beforehand, so they will not know what the CN-NINM potential effect is.

Trial Locations (1)

J1H 4C4

Centre de recherche sur le vieillissement (CdRV), Sherbrooke

All Listed Sponsors
collaborator

Chronic Pain Center of Excellence for Canadian Veterans

UNKNOWN

lead

Université de Sherbrooke

OTHER

NCT07137845 - Virtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans | Biotech Hunter | Biotech Hunter