Novel Thin Bronchoscope Versus Ultrathin Bronchoscope for the Diagnosis of Peripheral Pulmonary Nodules

NANot yet recruitingINTERVENTIONAL
Enrollment

465

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

July 31, 2026

Study Completion Date

August 31, 2026

Conditions
Lung Cancer (Diagnosis)
Interventions
DEVICE

Ultrathin bronchoscope (UTB)

A UTB will be used to perform white light bronchoscopy, then the rEBUS probe was inserted into the working channel and advanced to the PPL to obtain a rEBUS view per the navigation path created by VBN workstation. The probe will be withdrawn from the working channel when an optimal rEBUS view obtained. A 1.5-mm biopsy forceps and 1.4-mm cytology brush will be used to collect samples through the working channel.

DEVICE

Thin bronchoscope (TB1)

A thin bronchoscope will be used to perform white light bronchoscopy. A biopsy kit, including a 1.95-mm outer diameter guide sheath, 1.5-mm biopsy forceps, and 1.4-mm cytology brush, will be used to obtain samples with the guidance of VBN.

DEVICE

Thin bronchoscope (TB2)

A thin bronchoscope will be used to perform white light bronchoscopy. A biopsy kit, including a 2.55-mm outer diameter guide sheath, 1.9-mm biopsy forceps, and 1.8-mm cytology brush, will be used to obtain samples with the guidance of VBN.

Trial Locations (5)

100034

Peking University First Hospital, Beijing

210009

Zhongda Hospital Southeast University, Nanjing

315020

The First Affiliated Hospital of Ningbo University, Ningbo

450003

Henan Provincial People's Hospital, Zhengzhou

Unknown

Shanghai Chest Hospital, Shanghai

All Listed Sponsors
lead

Shanghai Chest Hospital

OTHER