144
Participants
Start Date
July 30, 2025
Primary Completion Date
July 7, 2026
Study Completion Date
June 7, 2027
VE818
VE818, is an 11-strain bacterial consortium rationally designed by Vedanta Biosciences Inc., to displace enteropathogens and reduce intestinal inflammation in pregnant women
Placebo
Enteric capsules filled with approximately 400mg of microcrystalline cellulose (bulking agent)
Oral Vancomycin
Oral vancomycin in capsule form will be administered three times daily for 5 days at 250mg per dose. Because oral vancomycin is a non-absorbable antibiotic, the likelihood of systemic absorption is minimal and therefore, it is not associated with the adverse events attributable to the intravenous formulation
RECRUITING
Agence de Formation de Recherche et d'Expertise en Santé pour l'Afrique, Bobo-Dioulasso
Institut de Recherche en Sciences de la Santé (IRSS)
UNKNOWN
Agence de Formation, de Recherche & d'Expertise en Santé pour l'Afrique (AFRICSanté)
UNKNOWN
Bill and Melinda Gates Foundation
OTHER
University Ghent
OTHER