30
Participants
Start Date
August 1, 2025
Primary Completion Date
September 1, 2026
Study Completion Date
December 1, 2026
Active taVNS
Protocol uses a 25 Hz frequency with 500 μs pulse width in biphasic configuration, operating at a 1:1 duty cycle with current intensity set to the maximum tolerable level without inducing pain. The total stimulation duration is 60 minutes. The stimulation is combined with physical therapy focused on upper extremity function.
Sham taVNS
Physical therapy focused on upper extremity function with masking for transcutaneous vagus nerve stimulation
RECRUITING
Federal University of Pernambuco, Recife
Fundação de Amparo à Ciência e Tecnologia de Pernambuco
OTHER
Conselho Nacional de Desenvolvimento Científico e Tecnológico
OTHER_GOV
Universidade Federal de Pernambuco
OTHER