Efficacy of Trans-auricular Vagus Nerve Stimulation on Upper Extremity Motor Recovery in Stroke Survivors

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

September 1, 2026

Study Completion Date

December 1, 2026

Conditions
Stroke
Interventions
DEVICE

Active taVNS

Protocol uses a 25 Hz frequency with 500 μs pulse width in biphasic configuration, operating at a 1:1 duty cycle with current intensity set to the maximum tolerable level without inducing pain. The total stimulation duration is 60 minutes. The stimulation is combined with physical therapy focused on upper extremity function.

DEVICE

Sham taVNS

Physical therapy focused on upper extremity function with masking for transcutaneous vagus nerve stimulation

Trial Locations (1)

50670-901

RECRUITING

Federal University of Pernambuco, Recife

All Listed Sponsors
collaborator

Fundação de Amparo à Ciência e Tecnologia de Pernambuco

OTHER

collaborator

Conselho Nacional de Desenvolvimento Científico e Tecnológico

OTHER_GOV

lead

Universidade Federal de Pernambuco

OTHER

NCT07132021 - Efficacy of Trans-auricular Vagus Nerve Stimulation on Upper Extremity Motor Recovery in Stroke Survivors | Biotech Hunter | Biotech Hunter