30
Participants
Start Date
October 30, 2025
Primary Completion Date
April 15, 2026
Study Completion Date
April 15, 2026
Spatially Fractionated Radiotherapy (SFRT)
Several spherical volumes (with a diameter of 1 cm) are selected within the hypoxic area of the primary tumor. The distance between each spherical volume is 1.5 - 2 cm, and a high-dose radiotherapy of 12 Gy × 1F is delivered.
Tislelizumab, Carboplatin, Pemetrexed
For adenocarcinoma, pemetrexed (500 mg/m², day 1) + carboplatin (AUC 5, day 1) is used.
Tislelizumab, paclitaxel, Carboplatin
For NSCLC with pathological types other than adenocarcinoma, nab-paclitaxel (100 mg/m² on day 1 and day 8) + carboplatin (AUC 5, day 1) is used.
Nanchang City, Jiangxi Province, Nanchang
Second Affiliated Hospital of Nanchang University
OTHER