PERCIST Evaluation of Trastuzumab Deruxtecan in the Treatment of HER2 Low Breast Cancer

NANot yet recruitingINTERVENTIONAL
Enrollment

262

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

September 30, 2030

Conditions
Metastatic Breast CancerHER 2 Low-expressing Breast Cancer
Interventions
PROCEDURE

TAP CT-scan

Patient in the SOC arm will be followed by TAP CT-scan every 3 months, until progression or new treatment initiation or until 2 years whichever occurs first.

PROCEDURE

Bone scintigraphy

Patient in the SOC arm will be followed by bone scintigraphy every 3 months, until progression or new treatment initiation or until 2 years whichever occurs first.

PROCEDURE

18F-FDG PET-CT

Patient in the experimental arm will be followed by 18F-FDG PET-CT every 3 months, until progression or new treatment initiation or until 2 years whichever occurs first.

Trial Locations (1)

67033

ICANS, Strasbourg

All Listed Sponsors
lead

Centre Paul Strauss

OTHER