A Clinical Study of GO306 in Patients With Advanced Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Solid Tumor Malignancies
Interventions
DRUG

GO306

"Part 1: A 3+3 single-dose escalation phase:~Low-dose cohort: 3.0E+07 PFU; Intratumoral or intracavitary injection of GO306; Cohort Size: 3 subjects; Dosing Schedule: Single initial administration.~Medium-dose cohort: 3.0E+08 PFU; Intratumoral or intracavitary injection of GO306; Cohort Size: 3 subjects; Dosing Schedule: Single initial administration.~High-dose cohort: 1.0E+09 PFU; Intratumoral or intracavitary injection of GO306; Cohort Size: 3 subjects; Dosing Schedule: Single initial administration.~Part 2: A multiple-dose expansion phase at the RP2D level to explore preliminary efficacy in specific tumor type:~RP2D; Intratumoral or intracavitary injection of GO306; Cohort Size: 20 subjects in specific tumor type; Dosing Schedule: QW or Q2W administration."

Trial Locations (4)

Unknown

RECRUITING

The First Affiliated Hospital of Anhui Medical University, Hefei

RECRUITING

Fujian Cancer Hospital, Fuzhou

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

NOT_YET_RECRUITING

Hunan Cancer Hospital, Changsha

All Listed Sponsors
lead

GeneSail Biotech (Shanghai) Co., Ltd.

INDUSTRY

NCT07128914 - A Clinical Study of GO306 in Patients With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter