NCT07126639 - A Study on the Short-course Treatment Regimen Containing Pretomanid for Drug-resistant Tuberculosis | Biotech Hunter

Enrollment

200

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2028

Conditions

Efficacy and Safety

Interventions

DRUG

bedaquiline

Administer 400 mg orally once daily for the first two weeks, followed by 200 mg orally three times a week for the subsequent 22 weeks.

DRUG

Pretomanid (Pa)

Administer 200 mg orally once daily for six months.

DRUG

linezolid

Administer 600 mg orally once daily for six months.

DRUG

Moxifloxacin (M)

Administer 400 mg orally once daily for six months.

DRUG

Delamanid (D)

Administer 100 mg orally twice daily for six months.

DRUG

Levofloxacin

Administer 800 mg orally once daily for six months.

DRUG

clofazimine

Administer 100 mg orally once daily for six months.

All Listed Sponsors

lead

Wuhan Pulmonary Hospital

OTHER