Impact of RFA on Esophageal Distensibility and Mucosal Impedance

RecruitingOBSERVATIONAL
Enrollment

10

Participants

Timeline

Start Date

August 19, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

July 31, 2027

Conditions
Dysplastic Barrett's EsophagusRadiofrequency AblationBarrett Esophagus
Interventions
DIAGNOSTIC_TEST

Radiofrequency ablation alone

If there is no evidence of nodularity, these patients will undergo RFA. Clinical biopsies utilizing a large-capacity biopsy forceps (Radial Jaw 4, Boston Scientific, Marlborough, MA) are obtained. RFA may be delivered through several devices under the BarrX RFA System (Medtronic USA, Minnetonka, MN), including a circumferential balloon catheter (Halo 360; figure 1), or over the scope focal catheter (Halo 90 or 60). The Halo 360 treats a circumferential 4 cm segment at a time, whereas the focal catheters treat a 1.3x2 cm (Halo 90) or 1.0x1.5 cm (Halo 60) area.

Trial Locations (1)

55905

RECRUITING

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER

NCT07126535 - Impact of RFA on Esophageal Distensibility and Mucosal Impedance | Biotech Hunter | Biotech Hunter