134
Participants
Start Date
October 1, 2025
Primary Completion Date
October 31, 2029
Study Completion Date
October 31, 2030
focal high-intensity focused ultrasound therapy combined with standard novel hormonal therapy
The participants in the intervention arm will receive HIFU combined with standard NHT. Depending on the location of the lesion, tumor load and the pathological conditions, hemicglandular ablation or focal ablation was selectively administered. The safe boundary was set at 3mm, with a power of 300W and a pulse width of 30ms. Novel endocrine therapy was given after HIFU treatment
Standard novel hormonal therapy only
Participants in the control arm will receive standard NHT.
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
OTHER