18
Participants
Start Date
July 1, 2022
Primary Completion Date
November 29, 2022
Study Completion Date
December 4, 2022
Botulinum toxin guided by ultrasonography and anatomical references
The botulinum neurotoxin (BoNT) will be calculated according to the weight of each patient. It will be injected in four places: two of them into the medial gastrocnemius and the other two into the lateral gastrocnemius. For medial gastrocnemius muscle, ¼ of the dose will be injected into the muscle belly at the 25% of the distance between the popliteal fossa and the intermalleolar line. Another ¼ will be injected into the muscle belly at the 35% of the previously mentioned distance. For lateral gastrocnemius, ¼ of the dose will be injected into the muscle belly at the 20% of the distance between the popliteal fossa and the intermalleolar line. The remaining ¼ of the dose will be injected into the muscle belly at the 30% of the previously described distance. All patients will conduct the same physical therapy program and under the direction of the same team of physical therapists. This program will begin two weeks after receiving the BoNT injection.
Botulinum neurotoxin guided by ultrasonography and in vivo location of innervation zones guided by high-density electromyography
The botulinum neurotoxin (BoNT) will be calculated according to the weight of each patient. It will be injected in eight places: four will be located in vivo for gastrocnemius medialis and four for gastrocnemius lateralis. These places will correspond to innervation zones located by high-density electromyography in different zones of each muscle. Thus, each of the eight located innervation zones will receive 1/8 of the calculated dose for the gastrocnemius muscle. All patients will conduct the same physical therapy program and under the direction of the same team of physical therapists. This program will begin two weeks after receiving the BoNT injection.
Universidad de los Andes, Santiago
Instituto Nacional de Rehabilitación Pedro Aguirre Cerda, Santiago
Fondo Nacional de Desarrollo Científico y Tecnológico, Chile
OTHER_GOV
Instituto Nacional de Rehabilitación Pedro Aguirre Cerda
UNKNOWN
Universidad de los Andes, Chile
OTHER