Alpha-Blockers Prior to Ureteral Access Sheath Placement in Flexible Ureteroscopy: A Randomized Prospective Study

PHASE4RecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

January 1, 2024

Primary Completion Date

January 1, 2026

Study Completion Date

February 1, 2026

Conditions
NephrolithiasisAlpha BlockerUreteral Access Sheath
Interventions
DRUG

Experimental: Alpha-blocker group

Participants in the experimental arm will receive an oral alpha-blocker (tamsulosin 0.4 mg) once daily for 7 consecutive days before undergoing flexible ureterorenolithotripsy. The medication is intended to relax ureteral smooth muscle fibers, potentially facilitating the insertion of the ureteral access sheath and reducing the need for a secondary procedure. The dose, route, and timing are standardized for all participants in this arm.

DRUG

No intervention (observational study)

Participants in this arm will undergo flexible ureterorenolithotripsy without receiving any alpha-blocker prior to surgery. All other perioperative care and surgical procedures will follow the same protocol as the experimental group.

Trial Locations (1)

09060-870

RECRUITING

Centro Universitário FMABC, Santo André

All Listed Sponsors
lead

Pedro de Figueiredo Buchalla

OTHER