Allogeneic CD7 CAR γδ T Cells Therapy Recurrent/Refractory Leukemia

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

August 18, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Leukemia
Interventions
BIOLOGICAL

CD7 CAR-γδT cell(QH106)

Allogenic CD7 CAR-γδT cell,Intravenous on day0; dose escalation (3+3) : dose 1 (1 × 10\^8 CAR+ cells) , dose 2 (3 × 10\^8CAR+ cells/kg,dose 3 (6× 10\^8 CAR+ cells);

DRUG

Fludarabine (FLU)

Intravenous fludarabine 30\~50 mg/m\^2/day on days-5, -4, and -3;

DRUG

Cyclophosphamide (CTX)

Intravenous cyclophosphamide 500\~1000 mg/m\^2/day on days -5, -4, and -3.

All Listed Sponsors
lead

Anhui Provincial Hospital

OTHER_GOV