34
Participants
Start Date
September 10, 2025
Primary Completion Date
December 30, 2027
Study Completion Date
December 30, 2029
lparomlimab and Tuvonralimab Injection in Combination with HAIC and bevacizumab
Iparomlimab and Tuvonralimab Injection(Q1706): 7.5 mg/kg, q3w, given on Day 1 (±7 days) of each 21-day cycle; Bevacizumab: 7.5 mg/kg, q3w, administered on Day 1 (±7 days) of each 21-day cycle; HAIC:Oxaliplatin 85 mg/m² via arterial infusion over 2-3 hours, Levoleucovorin 200 mg/m² via arterial infusion over 1-2 hours, 5-Fluorouracil 400 mg/m² via arterial bolus injection, followed by continuous arterial infusion of 2400 mg/m² over 23 hours, q3w, with the treatment interval not exceeding 4 weeks.
Tianjin Medical University Cancer Institute and Hospital
OTHER