A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine, and Digoxin

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 9, 2025

Primary Completion Date

April 5, 2026

Study Completion Date

April 5, 2026

Conditions
Healthy Volunteers
Interventions
DRUG

KarXT

Specified dose on specified days

DRUG

Midazolam

Specified dose on specified days

DRUG

Fexofenadine

Specified dose on specified days

DRUG

Digoxin

Specified dose on specified days

Trial Locations (1)

66219-9746

Local Institution - 0001, Lenexa

Sponsors
All Listed Sponsors
lead

Karuna Therapeutics

INDUSTRY