37
Participants
Start Date
August 31, 2025
Primary Completion Date
August 31, 2027
Study Completion Date
December 31, 2028
Palliative radiotherapy
Conventional fractionation, low-dose hypofractionated radiotherapy, or high-dose hypofractionated radiotherapy may be employed.
Iparomlimab and tuvonralimab
5 mg/kg, intravenously infused on Day 1 of each cycle, administered every 3 weeks (with each cycle defined as 21 days).
TAS-102
35 mg/m², orally twice daily on Days 1 to 5 and Days 8 to 12 of each cycle, with each cycle spanning 28 days (4 weeks).
Bevacizumab
7.5 mg/kg via intravenous infusion on Day 1 of each 21-day cycle.
Jinan Central Hospital, Jinan
Jinan Central Hospital
OTHER