Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

July 14, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

January 31, 2027

Conditions
FatigueBreast Cancer Female
Interventions
OTHER

Exercise Therapy Arm (ET)

Consists of a self-supervised individualized exercise prescription by the rehabilitation professional consisting of aerobic (e.g. brisk walking / cycling) and resistance training exercises, customized by patient preference.

OTHER

Experimental: Exercise Therapy (ET) plus Cognitive Behavioural Therapy (CBT)

Consists of four major components adapted from previous studies,13,15,16 and delivered by qualified and trained study psychologists. First, the ABC model of cognitive behavioural therapy (A: activating events, B: beliefs, C: consequences) will be taught and applied to identify negative, unhelpful beliefs and the emotional, behavioural and physical consequences of those beliefs. Second, patients were taught behavioural strategies to manage fatigue (e.g. sleep hygiene, activity scheduling). Lastly, participants will be guided to reformulate dysfunctional cognitions regarding fatigue, improve coping strategies in relation to significant others (e.g. family, friends) and set goals.

Trial Locations (4)

168583

RECRUITING

National Cancer Centre, Singapore (NCCS), Singapore

169608

RECRUITING

Singapore General Hospital, Singapore

529889

RECRUITING

NCCS Satellite Clinic @ Changi General Hospital, Singapore

544886

RECRUITING

NCCS Satellite Clinic @ Sengkang General Hospital, Singapore

All Listed Sponsors
collaborator

Singapore Cancer Society

OTHER

collaborator

Singapore General Hospital

OTHER

lead

National Cancer Centre, Singapore

OTHER