PERSONAE - a Personalized Online Treatment of Depression

NARecruitingINTERVENTIONAL
Enrollment

175

Participants

Timeline

Start Date

June 10, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

February 28, 2027

Conditions
Depression - Major Depressive Disorder
Interventions
BEHAVIORAL

Personalized iCBT for depression

"Participants receive 12 sessions of personalized treatment in an online iCBT program. The treatment includes the option for weekly written feedback from a psychologist, or video-based interventions depending on the participant's current status. The content of the 12-week program is tailored to the participant's individual symptom profile.~The treatment incorporates elements from standard Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT), Compassion-Focused Therapy (CFT), and Positive Activity Interventions (PAT).~The program consists of nine modules, each targeting a specific area:~Rumination,~Anhedonia,~Tearfulness and emotional regulation,~Sleep problems,~Difficulty concentrating,~Eating issues,~Low energy,~Social withdrawal,~Self-critical thinking,~The treatment concludes with support aimed at preventing relapse."

BEHAVIORAL

Standard iCBT

"Standard iCBT consisting of a one size fits all progression of cognitive behavioral therapy over 12 weeks. This includes:~Introduction to Online Cognitive Behavioral Therapy~Start of Treatment~Rumination~Activity Monitoring~Activity Planning~Cognitive Restructuring~Behavioral Experiment I~Behavioral Experiment II~Core Beliefs I~Core Beliefs II~Relapse Prevention"

Trial Locations (1)

5000

RECRUITING

Center for Digital Psychiatry, Odense

All Listed Sponsors
lead

Region of Southern Denmark

OTHER

NCT07113548 - PERSONAE - a Personalized Online Treatment of Depression | Biotech Hunter | Biotech Hunter