NCT07113106 - Dose Escalation Trial of CD40.Pan.CoV Vaccine, Adjuvanted or Not, as a Booster in Adult Healthy Volunteers | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

June 18, 2025

Primary Completion Date

June 25, 2026

Study Completion Date

June 25, 2027

Conditions

Healthy Volunteers

Interventions

BIOLOGICAL

CD40.Pan.CoV Low dose(0.25mg)

SC Injection in deltoid of Low dose (LD; 0.25 mg) CD40.Pan.CoV vaccine non adjuvanted at Day 0.

BIOLOGICAL

CD40.Pan.CoV Low dose (0,25mg) adjuvanted with Hiltonol®

SC injection in deltoid of LD (0.25 mg) CD40.Pan.CoV vaccine Hiltonol® adjuvanted at Day 0.

BIOLOGICAL

CD40.Pan.CoV High dose (1mg)

SC injectionin deltoid of High dose (HD; 1mg) CD40.Pan.CoV vaccine non adjuvanted at Day 0.

BIOLOGICAL

CD40.Pan.CoV High dose (1mg) adjuvanted with Hiltonol®

SC injection in deltoid of HD (1mg) CD40.Pan.CoV vaccine Hiltonol® adjuvanted at Day 0.

Trial Locations (7)

14033

NOT_YET_RECRUITING

Centre de Recherche Clinique CHU de Caen Normandie, Caen

44093

NOT_YET_RECRUITING

CIC 1413 CHU de Nantes, Nantes

59037

NOT_YET_RECRUITING

CIC 1403 CHU de Lille, Lille

63000

NOT_YET_RECRUITING

CIC 1405 CHU Clermont Ferrand, Clermont-Ferrand

75014

NOT_YET_RECRUITING

CIC 1417 Cochin-Pasteur Hôpital Cochin, Paris

75475

NOT_YET_RECRUITING

CIC 1427 Hôpital St Louis, Paris

94010

RECRUITING

Hôpital Henri Mondor, Créteil

All Listed Sponsors

collaborator

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

collaborator

Enno DC

UNKNOWN

collaborator

Unité Mixte de Service 54 Methods and Applied Research for Trials (UMS 54 MART)

UNKNOWN

lead

ANRS, Emerging Infectious Diseases

OTHER_GOV