Identification of Clinical, Genetic and Immunological Factors Involved in the Development of Severe Bacterial Infections in Pediatrics

Not yet recruitingOBSERVATIONAL
Enrollment

1,401

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

April 1, 2027

Study Completion Date

April 1, 2029

Conditions
Severe Bacterial Infections
Interventions
OTHER

Extended phenotyping

Extended phenotyping (analysis performed at Nantes University Hospital, MANDATORY DELIVERY WITHIN 24 HOURS) = 1 EDTA 3 mL tube for patients included in Nantes.

OTHER

Blood sample for WES

Blood sample for WES : 1 x 3 mL EDTA tube (if not included in DIABACT IV biocollection)

OTHER

Blood sample for PBMC freezing

Blood sample for PBMC freezing integrated into the biocollection: 1 EDTA tube = 3 mL

OTHER

POPC score evaluation

Assessment of POPC score (Pediatric Overall Performance Category)

OTHER

Questionnaire completion

"Questionnaires completed by parents or children:~* SDQ~* PedSQL4.0"

Trial Locations (1)

44093

Nantes University Hospital, Nantes

All Listed Sponsors
collaborator

Center for Research in Transplantation and Translational Immunology (UMR_S 1064)

UNKNOWN

lead

Nantes University Hospital

OTHER

NCT07111793 - Identification of Clinical, Genetic and Immunological Factors Involved in the Development of Severe Bacterial Infections in Pediatrics | Biotech Hunter | Biotech Hunter