Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical Trial

PHASE4RecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

March 31, 2028

Study Completion Date

March 31, 2029

Conditions
Lacunar StrokeStrokeIschemic Stroke
Interventions
DRUG

rt-PA

Recombinant tissue-plasminogen activator treatment. Low-dose (0.6mg/kg) alteplase will be given because this dosage is the only dosage approved in Japan.

DRUG

DAPT

Dual antiplatelet therapy with aspirin 200mg and clopidogrel 300mg.

Trial Locations (13)

Unknown

RECRUITING

Fukuoka Red Cross Hospital, Fukuoka

RECRUITING

Ota Memorial Hospital, Fukuyama

RECRUITING

Kagoshima City Hospital, Kagoshima

RECRUITING

Kagoshima Medical Center, Kagoshima

RECRUITING

Shioda Hospital, Katsuura

RECRUITING

Kohnan Hospital, Sendai

RECRUITING

Nippon Medical School Tamanagayama hospital, Tama

RECRUITING

Dokkyo Medical University Hospital, Tochigi

RECRUITING

Tokushima University Hospital, Tokushima

RECRUITING

Juntendo University Hospital, Tokyo

RECRUITING

Nippon Medical School hospital, Tokyo

RECRUITING

Tokyo Saiseikai Central Hospital, Tokyo

RECRUITING

Juntendo University Urayasu Hospital, Urayasu

Sponsors
All Listed Sponsors
collaborator

Japan Research Foundation for Clinical Pharmacology

UNKNOWN

collaborator

Takeda Science Foundation - Medical Research Grant

UNKNOWN

lead

Nippon Medical School

OTHER

NCT07111559 - Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical Trial | Biotech Hunter | Biotech Hunter