NCT07111130 - Restoring Bile Acid Homeostasis Via Lifestyle Adjustments to Prevent the Development of Liver Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 31, 2026

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2027

Conditions

Liver Diseases

Interventions

OTHER

12-week Lifestyle Intervention

Eligible participants within the existing ELEGANCE cohort will undergo a structured 12-week lifestyle intervention comprising a low-carbohydrate, high-fibre dietary plan and a prescribed physical activity program targeting at least 150 minutes of moderate-intensity exercise per week. Standardized meal provision and wearable fitness tracking devices will be used to support adherence throughout the intervention period.

Trial Locations (14)

119074

National University Hospital, Singapore

150163

SingHealth Polyclinics - Bukit Merah, Singapore

168583

National Cancer Center Singapore, Singapore

168937

SingHealth Polyclinics - Outram, Singapore

169608

Singapore General Hospital, Singapore

308433

Tan Tock Seng Hospital, Singapore

440080

SingHealth Polyclinics - Marine Parade, Singapore

469662

SingHealth Polyclinics - Bedok, Singapore

519466

SingHealth Polyclinics - Pasir Ris, Singapore

529203

SingHealth Polyclinics - Tampines, Singapore

529889

Changi General Hospital, Singapore

544886

Sengkang General Hospital, Singapore

545025

SingHealth Polyclinics - Sengkang, Singapore

820681

SingHealth Polyclinics - Punggol, Singapore

All Listed Sponsors

collaborator

Perspectum

INDUSTRY

collaborator

BUZUD Pte Ltd

UNKNOWN

collaborator

Asian Microbiome Library (AMiLi) Pte Ltd

UNKNOWN

lead

National Cancer Centre, Singapore

OTHER