The Pilot Study of the Utilization of Suggested Immobilization Test (SIT) for Diagnostic Confirmation of Restless Leg Syndrome in Thai Population

NANot yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

December 31, 2026

Conditions
Restless Leg Syndrome
Interventions
PROCEDURE

A suggested immobilization test (SIT)

The Suggested Immobilization Test (SIT) is a provocative test. RLS symptoms (urge to move the leg and leg paresthesia) are primarily observed during wakefulness, especially at rest, in the evening, and/or during the night. During the test, the patient remains in a bed (or a reclining chair), at a 45° angle with legs outstretched. Originally, the SIT only quantified leg motor activity. Since 2002, it also includes the assessment of leg discomfort, which is estimated by the patient every 5 min, on a 100-mm horizontal visual analogue scale. Leg movements are quantified using surface electromyography (EMG) from bilateral anterior tibialis muscles. Using these pathological thresholds, the clinical RLS/WED diagnosis is correctly predicted in 88% of subjects with a sensitivity of 82% and a specificity of 100%.

All Listed Sponsors
lead

Siriraj Hospital

OTHER

NCT07110961 - The Pilot Study of the Utilization of Suggested Immobilization Test (SIT) for Diagnostic Confirmation of Restless Leg Syndrome in Thai Population | Biotech Hunter | Biotech Hunter