Teclistamab-Daratumumab in AL Amyloidosis

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

October 31, 2031

Study Completion Date

October 31, 2033

Conditions
Amyloid Light-chain Amyloidosis
Interventions
DRUG

Teclistamab

Teclistamab is a T-cell redirecting bispecific antibody (BsAb) targeting CD3 on T-cells and B-cell maturation antigen (BCMA) on plasma cells.

DRUG

Daratumumab and Hyaluronidase-fihj

Daratumumab is an monoclonal antibody that targets the CD38 protein on the surface of myeloma cells.

Trial Locations (1)

10032

Columbia University Irving Medical Center, New York

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Janssen Pharmaceuticals

INDUSTRY

lead

Suzanne Lentzsch, MD

OTHER

NCT07110844 - Teclistamab-Daratumumab in AL Amyloidosis | Biotech Hunter | Biotech Hunter