Nutrition to Support Postoperative Recovery

NANot yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
Postoperative CarePostoperative ComplicationsCognitionNutritional AssessmentNutritional Intervention
Interventions
DIETARY_SUPPLEMENT

Nutritional Shake

The shake mixes will be dry shelf -stable powders prepared with ingredients readily available in the US food supply and contain a minimum of 990 mg total cocoa flavanols, with a profile to support general nutritional health including 10 g protein. Accordingly, each shake contains approximately 95 mg of caffeine, equivalent to a medium-sized cup of coffee. Based on prior studies of cognition, additional composition specifications are: 1600 mg DHA and up to 400 mg EPA and 550 mg choline; \>250 mg epicatechin and epigallocatechin (plant polyphenols); multivitamin/mineral fortification to ensure 50-100% of all essential micronutrients except calcium (to prevent competitive absorption with other divalent cations). Participants will be given a supply of pre-portioned daily servings upon discharge from the hospital, for 30 days after surgery.

OTHER

Nutritional Instructions Only

The control arm receives the Nutrition After Surgery instructions, which provide guidelines for healthy eating after surgery but not the nutritional shake. The intervention arm receives the same instructions along with the nutrition shake mix and accompanying postoperative supplementation

All Listed Sponsors
collaborator

Hitchcock Foundation

OTHER

lead

Dartmouth-Hitchcock Medical Center

OTHER

NCT07109505 - Nutrition to Support Postoperative Recovery | Biotech Hunter | Biotech Hunter