Study for Frail Patients With Newly Diagnosed Multiple Myeloma Treated With Daratumumab With Teclistamab or Talquetamab.

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

April 30, 2029

Study Completion Date

February 28, 2034

Conditions
Multiple Myeloma (MM)
Interventions
DRUG

Teclistamab

Teclistamab will be administered via a subcutaneous injection (SC), fixed duration and will be retreated until disease progression or intolerable toxicity.

DRUG

Talquetamab

Talquetamab will be administered via a subcutaneous injection (SC), fixed duration and will be retreated until disease progression or intolerable toxicity.

DRUG

Daratumumab

Dartumumab will be administered via a subcutaneous injection (SC), fixed duration and will be retreated until disease progression or intolerable toxicity.

All Listed Sponsors
collaborator

EMN Trial Office S.r.l. Impresa Sociale

OTHER

collaborator

HOVON - Dutch Haemato-Oncology Association

OTHER

collaborator

PETHEMA Foundation

OTHER

collaborator

Nordic Myeloma Study Group

OTHER

collaborator

Janssen Pharmaceutica N.V., Belgium

INDUSTRY

lead

European Myeloma Network B.V.

NETWORK