Closed-Loop Therapeutic Refinement Using Local Field Potentials in Parkinson's Disease

NANot yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

June 1, 2027

Study Completion Date

June 1, 2027

Conditions
Parkinson's Disease (PD)
Interventions
DEVICE

Conventional DBS

Treatment for a minimum of 2 to a maximum of 7 days with the patient's original conventional DBS (cDBS) settings.

DEVICE

Optimized conventional DBS

Treatment for a minimum of 2 to a maximum of 7 days with a previously optimized version of the patient's original conventional DBS (O-cDBS) settings.

DEVICE

Optimized adaptive DBS

Treatment for a minimum of 2 to a maximum of 7 days with previously optimized adaptive DBS (O-aDBS) settings.

Trial Locations (2)

1105AZ

Amsterdam UMC, Amsterdam

6229HX

Maastricht UMC+, Maastricht

All Listed Sponsors
collaborator

Maastricht University Medical Center

OTHER

collaborator

Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

OTHER

lead

HagaZiekenhuis

OTHER

NCT07105280 - Closed-Loop Therapeutic Refinement Using Local Field Potentials in Parkinson's Disease | Biotech Hunter | Biotech Hunter