NCT07100652View on ClinicalTrials.gov

Early Surfactant Administration at FiO₂ >0.25 Under NIPPV for RDS in Very Preterm Infants

NANot yet recruitingINTERVENTIONAL
Enrollment

384

Participants

Timeline

Start Date

January 1, 2026

Primary Completion Date

February 1, 2027

Study Completion Date

February 1, 2027

Conditions
Respiratory Distress Syndrome (&Amp; [Hyaline Membrane Disease])
Interventions
PROCEDURE

Threshold FiO₂

"Group 1 (Intervention Group) received the initial dose of pulmonary surfactant immediately upon reaching an inhaled oxygen concentration (FiO₂) \>0.25.~Group 2 (Control Group) received the initial dose of pulmonary surfactant as early as possible within 48 hours, but only when FiO₂ was titrated to \>0.3 based on the infant's clinical condition."

Trial Locations (1)

Unknown

Jiangxi Maternal and Child Health Hospital, Nanchang

All Listed Sponsors
collaborator

Jiangxi Maternal and Child Health Hospital

OTHER

lead

Jiulongpo No.1 People's Hospital

OTHER

NCT07100652 - Early Surfactant Administration at FiO₂ >0.25 Under NIPPV for RDS in Very Preterm Infants | Biotech Hunter | Biotech Hunter