NCT07098975View on ClinicalTrials.gov

Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial)

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

154

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

November 30, 2027

Study Completion Date

July 31, 2028

Conditions
Preeclampsia (PE)Intrauterine Growth Restriction (IUGR)Placental Insufficiency
Interventions
DRUG

Pravastatin 40 mg

This study proposes administering a daily dose of 40 mg of pravastatin between 24 and 29.6 weeks of gestation to mothers diagnosed with preeclampsia and/or fetal growth restriction.

OTHER

Placebo

A visually identical but inactive pill (a placebo),

Trial Locations (2)

08025

Hospital de la Santa Creu i de Sant Pau, Barcelona

Unknown

Hospital Clínic de Barcelona, Barcelona

All Listed Sponsors
collaborator

Universitat Autonoma de Barcelona

OTHER

collaborator

Hospital Clinic of Barcelona

OTHER

collaborator

Hospital Universitari Vall d'Hebron Research Institute

OTHER

lead

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

OTHER