NCT07097142 - Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study | Biotech Hunter

Enrollment

486

Participants

Timeline

Start Date

August 14, 2025

Primary Completion Date

May 31, 2030

Study Completion Date

May 31, 2030

Conditions

Bladder Cancer

Interventions

RADIATION

Hypofractionated Radiation Therapy

Undergo hypofractionated radiation therapy

DRUG

Cisplatin

Given IV

DRUG

Gemcitabine

Given IV

DRUG

Mitomycin

Given IV

DRUG

Fluorouracil

Given IV

PROCEDURE

Computed Tomography

Undergo CT scan

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

PROCEDURE

Positron Emission Tomography

Undergo PET scan

PROCEDURE

Biospecimen Collection

Undergo blood, tissue, and urine sample collection

OTHER

Survey Administration

Ancillary studies