80
Participants
Start Date
November 30, 2025
Primary Completion Date
November 30, 2029
Study Completion Date
May 31, 2030
Temporo-masseteric Nerve Block Injection
The TMNB injection/placebo will be administered by the Principal Investigator. The injection will only be delivered on Day 2 on the side/s of significant jaw muscle pain. Following disinfection of skin overlying the suprazygomatic injection site, a single carpule of 1.8 ml 2% lidocaine with 1:100,000 epinephrine will be delivered using a 25- or 27- gauge 30 mm needle). The injection site will be approximately a centimeter above the zygomatic arch, and a centimeter behind the palpable posterior border of the frontal process of the zygomatic bone. The needle will be directed at a 45-degree downward angle, directed medially along the coronal plane. At the depth of insertion of the needle, the local anesthetic/placebo will be delivered.
Oral Pain Medications only
For participants with jaw muscle pain to palpation \<5 NRS score, no additional injection will be given. The participant will take the recommended pain medications as described.
Rutgers School of Dental Medicine, Newark
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Rutgers, The State University of New Jersey
OTHER