MELAFERT: Impact of Adjuvant Therapy on FERTility in Patients With Resected MELAnoma at High Risk of Relapse.

RecruitingOBSERVATIONAL
Enrollment

270

Participants

Timeline

Start Date

August 4, 2025

Primary Completion Date

August 1, 2028

Study Completion Date

August 31, 2032

Conditions
MelanomaFertility
Interventions
DRUG

Dabrafenib + Trametinib

There is no different use in the clinical application of the drugs reported above, the study on fertility will be implemented in the women with completely resected melanoma enrolled in the study

DRUG

Pembrolizumab

There is no different use in the clinical application of the drugs reported above, the study on fertility will be implemented in the women with completely resected melanoma enrolled in the study

DRUG

Nivolumab

There is no different use in the clinical application of the drugs reported above, the study on fertility will be implemented in the women with completely resected melanoma enrolled in the study

OTHER

Observation

Patients who will not initiate adjuvant therapy, but will undergo observation (due to refusal, comorbidities, other reasons).

Trial Locations (10)

10126

NOT_YET_RECRUITING

Università di Torino - Clinica Dermatologica, Torino

20861

NOT_YET_RECRUITING

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan

35128

NOT_YET_RECRUITING

IOV Istituto Oncologico Veneto, Padua

41125

NOT_YET_RECRUITING

Azienda Ospedaliero-Universitaria, Modena, Modena

53035

NOT_YET_RECRUITING

Università degli Studi di Siena - U.O.C. Immunoterapia Oncologica Azienda Ospedaliera Universitaria Senese, Siena

70122

NOT_YET_RECRUITING

"Ospedale Oncologico Giovanni Paolo II", Bari

80016

NOT_YET_RECRUITING

"Istituto Nazionale Tumori Fondazione Pascale", Napoli

Unknown

NOT_YET_RECRUITING

IRCCS Ospedale Policlinico San Martino, Oncologia Medica 2, Genova

06132

RECRUITING

Azienda Ospedaliera Santa Maria della Misericordia - Unità di Oncologia Medica., Perugia

00168

NOT_YET_RECRUITING

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma

All Listed Sponsors
lead

Intergruppo Melanoma Italiano

OTHER