Home Transcranial Direct Current Stimulation (tDCS) to Enhance Functional Recovery

NANot yet recruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

December 31, 2030

Study Completion Date

December 31, 2031

Conditions
StrokeNeurodegenerationBrain Tumor
Interventions
DEVICE

Soterix® tDCS - Home treatment

"Participants will receive transcranial direct current stimulation (tDCS) via the Soterix device at an intensity of 2 mA for 20 minutes per session, with slow ramp-up and ramp-down of the current.~Each participant will be asked to perform tDCS on weekdays for two-weeks (10 sessions total) or every other weekday for four weeks (12 sessions). The research team will decide on a number of therapy sessions depending on the patient's baseline condition and tolerance. Patients who receive 10 sessions of therapy over two weeks will have 4 weeks of washout. Patients who receive 12 sessions over four weeks will have 8 weeks of washout."

BEHAVIORAL

Cognitive-linguistic therapy

Participants will be instructed to perform home activity based cognitive-linguistic task-based exercises. Each participant will be asked to perform tDCS concurrently with individualized activity based cognitive-linguistic therapy on weekdays for two-weeks (10 sessions total) or every other weekday for four weeks (12 sessions)

DEVICE

Soterix® tDCS - Lab treatment

Participants will receive transcranial direct current stimulation (tDCS) in person, via the same Soterix device the home based participants will use at an intensity of 2 mA for 20 minutes per session, with slow ramp-up and ramp-down of the current. They will undergo 12 sessions over four weeks.

Trial Locations (1)

55905

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER

NCT07091396 - Home Transcranial Direct Current Stimulation (tDCS) to Enhance Functional Recovery | Biotech Hunter | Biotech Hunter