PRF vs. Graftless Sinus Lift With Implant Placement

PHASE1Enrolling by invitationINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

February 1, 2025

Primary Completion Date

August 31, 2025

Study Completion Date

August 31, 2025

Conditions
Maxillary Sinus Floor AugmentationAlveolar Bone LossAtrophyPlatelet-rich FibrinDental Implant
Interventions
PROCEDURE

Graftless Transcrestal Sinus Floor Elevation with Immediate Implant Placement

This intervention involves a minimally invasive internal (crestal) sinus lift performed without the use of any grafting material. The sinus membrane is elevated using sequential osteotomy drills, and a dental implant is immediately placed into the prepared site. The implant fixture acts as a tent pole, maintaining the lifted membrane and allowing for spontaneous bone regeneration through blood clot formation alone. This graftless method eliminates the need for additional biomaterials and is intended for patients with residual alveolar bone height of 5-7 mm

BIOLOGICAL

Platelet-Rich Fibrin (PRF)-Assisted Transcrestal Sinus Floor Elevation with Immediate Implant Placement

This intervention utilizes autologous platelet-rich fibrin (PRF) as the sole grafting material during transcrestal sinus floor elevation. PRF is prepared from the patient's own venous blood using centrifugation and inserted into the osteotomy site after sinus membrane elevation. A dental implant is placed simultaneously to support the sinus membrane and stabilize the graft. The biologically active PRF matrix provides a scaffold rich in growth factors (e.g., TGF-β, PDGF, VEGF), promoting accelerated healing and enhanced bone formation beneath the elevated sinus floor. This technique is performed in a single-stage procedure, eliminating the need for synthetic or allogeneic grafts.

Trial Locations (1)

11512

College of Dentistry, Dar AlUloom University, Riyadh

All Listed Sponsors
lead

Dar Al Uloom University

OTHER