The Effect-site Concentration of Remifentanil Blunting Endotracheal Intubation Responses During Anesthesia Induction With Lidocaine or Sufentanil Combined With Etomidate: A Randomized Controlled Study

NARecruitingINTERVENTIONAL
Enrollment

99

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

July 30, 2026

Study Completion Date

July 30, 2026

Conditions
Hemodynamics
Interventions
DRUG

Intravenous normal saline (NS 0.9)

Under target-controlled infusion (TCI) of remifentanil, anesthesia induction is performed using placebo (normal saline) combined with etomidate (0.3 mg/kg).

DRUG

intravenous sufentanil

Under target-controlled infusion (TCI) of remifentanil, anesthesia induction is performed using sufentanil (0.2μg/kg) combined with etomidate (0.3 mg/kg).

DRUG

Intravenous lidocaine

Under target-controlled infusion (TCI) of remifentanil, anesthesia induction is performed using lidocaine (1.5 mg/kg) combined with etomidate (0.3 mg/kg).

Trial Locations (1)

Unknown

RECRUITING

Peking University Shenzhen Hospital, Shenzhen

All Listed Sponsors
lead

Peking University Shenzhen Hospital

OTHER

NCT07089173 - The Effect-site Concentration of Remifentanil Blunting Endotracheal Intubation Responses During Anesthesia Induction With Lidocaine or Sufentanil Combined With Etomidate: A Randomized Controlled Study | Biotech Hunter | Biotech Hunter