39
Participants
Start Date
July 31, 2025
Primary Completion Date
August 1, 2027
Study Completion Date
August 1, 2028
Sacituzumab Tirumotecan and Toripalimab
The dosing regimen for the combination of Sacituzumab Tirumotecan and Toripalimab is as follows: the recommended dose of Sacituzumab Tirumotecan is 5mg/kg, administered intravenously every 2 weeks, and Toripalimab is administered intravenously (without prophylactic medication), with a fixed dose of 240mg, and 3mg/kg is used for subjects with baseline body weight\<50kg. Each infusion lasts for 30 minutes (not less than 20 minutes, not more than 60 minutes), administered once every 2 weeks. The subjects will continue to receive combination therapy with Sacituzumab Tirumotecan and Toripalimab until the termination criteria are met.
RECRUITING
the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
OTHER