NCT07086677View on ClinicalTrials.gov

A Study to Learn About How a New Pneumococcal Vaccine Works in Adults

PHASE1RecruitingINTERVENTIONAL
Enrollment

372

Participants

Timeline

Start Date

July 22, 2025

Primary Completion Date

September 23, 2027

Study Completion Date

September 23, 2027

Conditions
Streptococcus Pneumoniae
Interventions
BIOLOGICAL

PG4 vaccine in Buffer 1 with low dose PA-001

Multivalent pneumococcal conjugate vaccine

BIOLOGICAL

PG4 in Buffer 1 with low dose PA-002

Multivalent pneumococcal conjugate vaccine

BIOLOGICAL

PG4 in Buffer 1 with high dose PA-001

Multivalent pneumococcal conjugate vaccine

BIOLOGICAL

PG4 vaccine in Buffer 1 with high dose PA-002

Multivalent pneumococcal conjugate vaccine

BIOLOGICAL

PG4 vaccine in Buffer 2

Multivalent pneumococcal conjugate vaccine

BIOLOGICAL

20-valent pneumococcal conjugate vaccine

(20vPnC)

BIOLOGICAL

Saline injection

Placebo

Trial Locations (5)

33012

NOT_YET_RECRUITING

Indago Research & Health Center, Inc, Hialeah

45212

RECRUITING

CTI Clinical Research Center, Cincinnati

66219

RECRUITING

Johnson County Clinical Trials, Lenexa

68134

RECRUITING

Velocity Clinical Research, Omaha, Omaha

92630

NOT_YET_RECRUITING

Orange County Research Center, Lake Forest

Sponsors

Lead Sponsor

Pfizer
All Listed Sponsors
lead

Pfizer

INDUSTRY