NCT07086287View on ClinicalTrials.gov

Evaluation of the Efficacy of rhBNP in Patients With Diuretic Resistance After Cardiac Surgery

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

June 30, 2028

Conditions
After Cardiac SurgeryDiuretic Resistance
Interventions
DRUG

rhBNP and standard basic treatment

After administering a bolus of rhBNP at 1.5-2 μg/kg intravenously, a maintenance dose of 0.0075-0.01 μg/kg/min is continuously infused intravenously for 72 hours, with the dosage adjusted based on blood pressure and heart rate; the control group receives standard basic treatment.

Trial Locations (1)

230000

the First Affiliated Hospital of Anhui Medical University, Hefei

All Listed Sponsors
lead

The First Affiliated Hospital of Anhui Medical University

OTHER