NCT07085624View on ClinicalTrials.gov

Early Optimization of Ceftazidime Regimen in Critical Care

NANot yet recruitingINTERVENTIONAL
Enrollment

128

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Infection in ICUSepsisSeptic ShockPseudomonas Aeruginosa Infection
Interventions
DRUG

ceftazidime

ceftazidime loading dose and maintenance dose

BIOLOGICAL

plasma ceftazidime dosage

"plasma ceftazidime dosage kinetics will be performed according to an optimal D- sampling plan (4 measurements per subject: T0+5min, T0+3h, T0+6h, T0+24h, PFIM software).~T0 corresponds to the time to administer the ceftazidime loading dose."

Trial Locations (8)

13915

CHU Nord, Médecine intensive et réanimation, Marseille

38043

CHU GRENOBLE, Médecine intensive, Grenoble

42055

CHU ST-ETIENNE - Médeine Intensive Réanimation, Saint-Etienne

CHU ST-ETIENNE, Médecine intensive Réanimation B, Saint-Etienne

CHU ST-ETIENNE, Réanimation Néphrologie, Saint-Etienne

69004

HCL Croix Rousse, Médecine intensive réanimation, Lyon

69437

HCL Hôpital Edouard Herriot, Médecine intensive et réanimation, Lyon

69495

HCL Hôpital Lyon Sud, Médecine intensive réanimation, Pierre-Bénite

All Listed Sponsors
collaborator

Direction Générale de l'Offre de Soins

OTHER_GOV

collaborator

GIRCI Auvergne Rhône-Alpes

UNKNOWN

lead

Centre Hospitalier Universitaire de Saint Etienne

OTHER

NCT07085624 - Early Optimization of Ceftazidime Regimen in Critical Care | Biotech Hunter | Biotech Hunter