Single Dose PCSK9 Inhibitor to Improve Cardiovascular Outcomes After PCI: A Pilot Study

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

352

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

June 30, 2030

Study Completion Date

July 31, 2030

Conditions
Coronary Artery Disease
Interventions
DRUG

PCSK9 inhibitor

Single dose of subcutaneous administration of PCSK9 inhibitors (evolocumab) after PCI in patients with coronary artery disease and elevated post-PCI lipid core burden (maxLCBI4mm ≥ 200).

DRUG

Standard Lipid-Lowering Therapy

Lipid-lowering therapy with high-intensity or maximally tolerated statins with or without ezetimibe, as per current clinical guidelines, excluding the use of PCSK9 inhibitors.

All Listed Sponsors
collaborator

DOTTER Inc.

UNKNOWN

lead

Hanyang University Seoul Hospital

OTHER