A Phase IIa Clinical Trial to Evaluate the Efficacy and Safety of Intravenous Infusion of hUC-MSCs in Patients With AIS

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

August 27, 2025

Primary Completion Date

March 5, 2026

Study Completion Date

December 5, 2026

Conditions
Acute Ischemic Stroke AIS
Interventions
DRUG

hUC-MSCs treatment (high dose)

2.0×10\^8 cells per infusion, single administration on D0. Infusion of cell medium placebo on Day 7 (±2 days), and Day 14 (±2 days).

DRUG

hUC-MSCs treatment (low dose)

1.0×10\^8 cells per infusion, 3 administrations, on Day 0, Day 7 (±2 days), and Day 14 (±2 days)

DRUG

Placebo

Cell medium, 3 administrations, on Day 0, Day 7 (±2 days), and Day 14 (±2 days)

Trial Locations (1)

100070

RECRUITING

Beijing Tiantan Hospital, Capital Medical University, Beijing

All Listed Sponsors
collaborator

Beijing Tiantan Hospital

OTHER

lead

Shenzhen Wingor Biotechnology Co., Ltd.

INDUSTRY

NCT07084012 - A Phase IIa Clinical Trial to Evaluate the Efficacy and Safety of Intravenous Infusion of hUC-MSCs in Patients With AIS | Biotech Hunter | Biotech Hunter