Faecal Autologous Capsule Transplantation for Type 1 Diabetes Mellitus

PHASE2RecruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

September 30, 2029

Study Completion Date

September 30, 2029

Conditions
Type 1 Diabetes MellitisType 1 Diabetes (T1D)Fecal Microbiota Therapy (FMT)
Interventions
BIOLOGICAL

freezedried autologous encapsulated fecal microbiota transplantation

The freezedried autologous encapsulated microbiota transplantation increases the exposure of the small intestine to the microbiota residing in the colon. Prior evidence was found that this has strong immunomodulatory effects leading to potential preservation of beta cell function in type 1 diabetes.

OTHER

placebo matching capsule without microbial content

this is the matching placebo capsule that looks from the outside identical to the actual treatment but does not contain the fecal microbiota.

Trial Locations (1)

Unknown

RECRUITING

Diabeter Centrum Amsterdam, Amsterdam

All Listed Sponsors
collaborator

Diabeter Centrum Amsterdam

UNKNOWN

lead

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER