Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait

RecruitingOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

August 23, 2022

Primary Completion Date

August 23, 2025

Study Completion Date

August 23, 2025

Conditions
Sickle Cell DiseaseSickle Cell Trait
Interventions
OTHER

Healthy volunteers without SCT

Participants will donate blood for serum bone turnover markers, complete blood count, calcium, phosphorus, albumin, parathyroid hormone, and hemoglobin electrophoresis. Participants will undergo a bone density evaluation and muscle mass measurement via dual-energy x-ray absorptiometry (DEXA) scanning. Participants will fill out dietary calcium intake and pain burden questionnaires. Participants will fill out a survey for frailty assessment, undergo 6-minute walk gait velocity and short physical performance battery (SPPB).

OTHER

Healthy volunteers with SCT

Participants will donate blood for serum bone turnover markers, complete blood count, calcium, phosphorus, albumin, parathyroid hormone, and hemoglobin electrophoresis. Participants will undergo a bone density evaluation and muscle mass measurement via dual-energy x-ray absorptiometry (DEXA) scanning. Participants will fill out dietary calcium intake and pain burden questionnaires. Participants will fill out a survey for frailty assessment, undergo 6-minute walk gait velocity and short physical performance battery (SPPB).

Trial Locations (1)

06030

RECRUITING

UConn Health, Farmington

All Listed Sponsors
lead

UConn Health

OTHER